Research & Innovation

A New Drug for Vulvodynia? What to Know About the Pudafensine Clinical Trial

A New Drug for Vulvodynia? What to Know About the Pudafensine Clinical Trial

There is no medication approved specifically for vulvodynia. Not a single one. John Connell and his team are trying to change that.In this episode, I sit down with John Connell, Chief Scientific Officer at MAC Clinical Research — one of...
Published
Apr 6, 2026
Duration
44:35
The Device Designed to Make Sex Less Painful: Pelva Founder Kelley on Vulvodynia & Vaginismus

The Device Designed to Make Sex Less Painful: Pelva Founder Kelley on Vulvodynia & Vaginismus

What if the answer to painful sex wasn't another dilator - but something genuinely novel? In this episode, Mathilde sits down with Kelley, co-founder of Pelva and a fellow woman with lived-experience  who went from primary vaginismus and...
Published
Mar 9, 2026
Duration
39:20
Solo: What the World's Top Sexual Medicine Conference Means for Women w/ Vulvovaginal & Pelvic Pain

Solo: What the World's Top Sexual Medicine Conference Means for Women w/ Vulvovaginal & Pelvic Pain

I just got back from the ISSWSH (International Society for the Study of Women's Sexual Health) annual meeting in Long Beach, California - and I couldn't wait to bring everything I heard straight to you. This solo episode is part conferen...
Published
Feb 19, 2026
Duration
36:11
From Black Box to Breakthrough: Dr. A. Goldstein on the Golden Era of Vulvodynia Research

From Black Box to Breakthrough: Dr. A. Goldstein on the Golden Era of Vulvodynia Research

For decades, vulvodynia was considered a mystery condition with few answers and limited treatment options. That's no longer the case.In this episode, Dr. Andrew Goldstein - Clinical Professor at George Washington University and one of th...
Published
Feb 9, 2026
Duration
51:49
Can Light Therapy Help Pelvic Pain? Science, Benefits & Expert Insights | Liz Frey

Can Light Therapy Help Pelvic Pain? Science, Benefits & Expert Insights | Liz Frey

If you're dealing with vaginismus or vulvodynia, you know how limited treatment options can feel - and how rarely we see real innovation in this space. That's why I was so intrigued when I discovered light therapy as a potential tool for...
Published
Feb 2, 2026
Duration
41:08